Total abdominal and pelvic radiation may be given, but only if the residual disease is less than 1/4 in. (0.5 cm) in diameter. Intra-abdominal radioactive phosphate may be given only if the residual disease is less than 1 mm in diameter.
If there is residual cancer larger than 3/4 in. (2 cm) in diameter or metastases outside the abdominal cavity, intravenous chemotherapy is used exclusively. The commonly used combinations are the same as used for Stage IIa, namely CT, CP, CAP, AP and CHAD.
Investigational Many investigational protocols are being used in the treatment of ovarian cancer:
• Intra-abdominal administration of single agents such as interferon-alpha , cisplatin , carboplatin , Ara-C ,
